The school has spacious and well equipped laboratories for Physics, Chemistry and Biology, Mathematics and Computer. Students are imparted practical education under the watchful eyes of the instructors and teachers.

The chemistry department of Sita Sharan Memorial School offers courses in Chemistry up to class X as per CBSE requirements and syllabus. All chemicals and equipments required for practicals and projects are provided. The lab has running water with ample storage area for chemicals, equipment and balances. The students are allotted their own experiment tables in batches and each such table contains every necessary reagent for experimental purpose. A full time, qualified lab attendant is also present to help the students during practicals.